IMIQUIMOD

Imiquimod is an immune-response modifier that stimulates interferon production to treat skin lesions such as warts and superficial cancers. Side effects include redness, swelling, irritation, and flu-like symptoms. Only GMP materials will be supplied, logistics all according to GDP.

Product Description


Mechanism of Action

IMIQUIMOD exhibits a multi-dimensional biochemical activity profile that affects cellular regulation at enzyme, receptor, and transcriptional levels. Its molecular interactions can alter phosphorylation cycles, modulate ionic homeostasis, influence mitochondrial respiration, and adjust redox-signaling pathways. Structural properties suggest specific affinity for regulatory proteins, enabling modulation of metabolic flux and cellular response thresholds.

Benefits and Advantages

This compound is suited for high-resolution mechanistic research, multiomics integration studies, receptor-binding experiments, enzyme-pathway mapping, and advanced pharmacodynamic modelling. It supports ROS-regulation assays, signalling-cascade analysis, cytoskeletaldynamics research, and metabolic adaptation models. Due to predictable biochemical behaviour, it is often used as a comparative reference in pathwayperturbation studies.

  • Useful in mechanistic pharmacology and biochemical modelling
  • Applicable in oxidative-stress, mitochondrial-function and signalling studies
  • Reliable for transcriptional and proteomic profiling
  • Supports SAR (structureactivity relationship) investigations

Side Effects and Risks

Potential risks include mitochondrial overload, ROS imbalance, inadvertent receptor crosstalk, disruption of ion-channel dynamics, and dose-dependent cytotoxicity. High exposure may trigger apoptosis, autophagy, or cellular stress-response activation. Controlled handling conditions and biosafety protocols are required for laboratory use.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C14H16N4

Molecular Weight

240.30 g/mol

CAS Number

99011-02-6

Storage Condition

Imiquimod topical cream should be stored at 4-25 °C; freezing should be avoided.

Solubility

Poorly soluble

Purity

Purity information is available upon request (COA).

Synonym

IMIQUIMOD; 99011-02-6; Aldara; Zyclara; 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine

IUPAC/Chemical Name

1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine

InChl Key

DOUYETYNHWVLEO-UHFFFAOYSA-N

InChl Code

InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)

References

https://pubchem.ncbi.nlm.nih.gov/compound/57469;

3D Conformer.

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