About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Galantamine hydrobromide is a reversible acetylcholinesterase (AChE) inhibitor that also allosterically modulates nicotinic acetylcholine receptors, enhancing cholinergic neurotransmission. This dual mechanism improves synaptic acetylcholine levels and receptor responsiveness.
Benefits and Advantages
Used in neurodegeneration models, AChE inhibition assays, cholinergic signalling research and cognitive-function studies.
Side Effects and Risks
Nausea, bradycardia, cholinergic overstimulation and GI upset. Handle as a potent neuroactive cholinesterase inhibitor.
Datasheet
| Molecular Formula | C17H22BrNO3 |
|---|---|
| Molecular Weight | 368.3 g/mol |
| CAS Number | 19453 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Galanthamine hydrobromide; Galantamine hydrobromide; 1953-04-4; Nivaline; Nivalin |
| IUPAC/Chemical Name | (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide |
| InChl Key | QORVDGQLPPAFRS-XPSHAMGMSA-N |
| InChl Code | InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1 |
| References |
3D Conformer.
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