About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Gaboxadol (THIP) is a potent GABA‑A receptor agonist with selectivity for extrasynaptic δ‑subunit‑containing receptors, producing sustained tonic inhibitory currents. This distinguishes its sedative and hypnotic profile from benzodiazepines, which primarily enhance synaptic GABA‑A activity.
Benefits and Advantages
Used in sleep‑state regulation research, tonic‑inhibition modelling, receptor‑subtype pharmacology and CNS drug‑development assays.
Side Effects and Risks
Risks include drowsiness, dizziness, confusion, altered sleep architecture and, at high doses, respiratory and CNS depression. Handle with CNS‑depressant precautions.
Datasheet
| Molecular Formula | C7H10N2O2 |
|---|---|
| Molecular Weight | 140.14 g/mol |
| CAS Number | 64603-91-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | gaboxadol; THIP; 64603-91-4; Gaboxadolum; MK-0928 |
| IUPAC/Chemical Name | 4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one |
| InChl Key | ZXRVKCBLGJOCEE-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C6H8N2O2/c9-6-4-1-2-7-3-5(4)10-8-6/h7H,1-3H2,(H,8,9) |
| References |
3D Conformer.
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