About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Gabexate is a synthetic serine‑protease inhibitor active against trypsin, kallikrein, plasmin and thrombin. By blocking proteolytic cascades, it attenuates coagulation, complement activation and inflammatory mediator release, especially in pancreatic and vascular systems.
Benefits and Advantages
Used in acute pancreatitis models, coagulation‑cascade modulation studies, protease‑inhibition assays and inflammatory mediator research.
Side Effects and Risks
Risks include hypotension, thrombophlebitis, hypersensitivity reactions and potential bleeding. Handle with serine‑protease inhibitor precautions and monitoring of coagulation parameters.
Datasheet
| Molecular Formula | C15H23N3O5 |
|---|---|
| Molecular Weight | 321.37 g/mol |
| CAS Number | 39492-01-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | gabexate; 39492-01-8; Gabexato; Gabexatum; ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate |
| IUPAC/Chemical Name | ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate |
| InChl Key | YKGYIDJEEQRWQH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C16H23N3O4/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18/h7-10H,2-6,11H2,1H3,(H4,17,18,19) |
| References |
3D Conformer.
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