GABADAXOL
Gabadaxol is a GABAA receptor agonist investigated for sleep disorders. Side effects include sedation, dizziness, and cognitive impairment. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Gabadaxol (gaboxadol derivative) is a selective extrasynaptic GABAA receptor agonist that preferentially activates subunitcontaining GABAA receptors, enhancing tonic inhibition rather than phasic synaptic currents. This produces distinct sedative and sleepmodulating effects.
Benefits and Advantages
Used in sleeparchitecture research, tonic vs. phasic GABAergic signalling studies, receptorsubtype pharmacology and CNS drugdiscovery models.
Side Effects and Risks
Risks include sedation, dizziness, ataxia, cognitive impairment and, at high doses, respiratory depression. Handle with CNSdepressant and GABAagonist precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C7H10N2O2 |
|---|---|
| Molecular Weight | 144.17 g/mol |
| CAS Number | 67469-80-5 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | 4-aminobutanamide |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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