FURAZOLIDONE

Furazolidone is a nitrofuran antibiotic disrupting bacterial DNA. Side effects include nausea, headache, and risk of MAOinhibition interactions. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 26610642d812 Category: Tag:

Product Description


Mechanism of Action

Furazolidone is a nitrofuran antimicrobial that is enzymatically reduced in susceptible microorganisms to highly reactive intermediates capable of damaging DNA, ribosomal proteins and other critical macromolecules. It interferes with carbohydrate metabolism and nucleicacid synthesis in bacteria and protozoa.

Benefits and Advantages

Used in GIpathogen research, nitrofuranredox pathway studies, DNAdamage response assays and protozoal infection models.

Side Effects and Risks

Risks include GI upset, hemolytic anemia in G6PDdeficient subjects, hypersensitivity reactions and potential carcinogenicity. Handle with nitrofuranclass cytotoxic and genotoxic precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C8H7N3O5

Molecular Weight

225.16 g/mol

CAS Number

67-45-8

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

furazolidone; 67-45-8; Nitrofurazolidone; Furazolidine; Nitrofuroxon

IUPAC/Chemical Name

3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one

InChl Key

PLHJDBGFXBMTGZ-WEVVVXLNSA-N

InChl Code

InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+

References

https://pubchem.ncbi.nlm.nih.gov/compound/5323714;

3D Conformer.

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