About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Furazolidone is a nitrofuran antimicrobial that is enzymatically reduced in susceptible microorganisms to highly reactive intermediates capable of damaging DNA, ribosomal proteins and other critical macromolecules. It interferes with carbohydrate metabolism and nucleic‑acid synthesis in bacteria and protozoa.
Benefits and Advantages
Used in GI‑pathogen research, nitrofuran‑redox pathway studies, DNA‑damage response assays and protozoal infection models.
Side Effects and Risks
Risks include GI upset, hemolytic anemia in G6PD‑deficient subjects, hypersensitivity reactions and potential carcinogenicity. Handle with nitrofuran‑class cytotoxic and genotoxic precautions.
Datasheet
| Molecular Formula | C8H7N3O5 |
|---|---|
| Molecular Weight | 225.16 g/mol |
| CAS Number | 67-45-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | furazolidone; 67-45-8; Nitrofurazolidone; Furazolidine; Nitrofuroxon |
| IUPAC/Chemical Name | 3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one |
| InChl Key | PLHJDBGFXBMTGZ-WEVVVXLNSA-N |
| InChl Code | InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+ |
| References |
3D Conformer.
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