FURIZALOLE
Furizazole is an antifungal agent inhibiting ergosterol synthesis. Side effects include GI upset, dizziness, and rare hepatic effects. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Furizazole is an imidazolelike azole antifungal with a nitrofuran moiety that inhibits fungal cytochrome P450dependent 14demethylase, blocking ergosterol biosynthesis and compromising cellmembrane integrity. Additional nitrofuranbased redox activity contributes to fungistatic or fungicidal effects.
Benefits and Advantages
Used in ergosterolpathway research, azole SAR studies, fungal redoxstress modelling and combination antifungal testing.
Side Effects and Risks
Potential hepatic enzyme elevation, GI disturbances, skin reactions and nitrofuranassociated genotoxicity concerns. Handle with azolenitrofuran dualmechanism precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C10H6Cl2N2O |
|---|---|
| Molecular Weight | 278.13 g/mol |
| CAS Number | 121776-33-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Furilazole; 121776-33-8; MON 13900; 3-(Dichloroacetyl)-5-(2-furanyl)-2,2-dimethyloxazolidine; Furilazole [ISO:BSI] |
| IUPAC/Chemical Name | 2,2-dichloro-1-[5-(furan-2-yl)-2,2-dimethyl-1,3-oxazolidin-3-yl]ethanone |
| InChl Key | MCNOFYBITGAAGM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C11H13Cl2NO3/c1-11(2)14(10(15)9(12)13)6-8(17-11)7-4-3-5-16-7/h3-5,8-9H,6H2,1-2H3 |
| References |
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