About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
5‑Fluorouracil (5‑FU) is a pyrimidine antimetabolite that inhibits thymidylate synthase and incorporates into RNA and DNA, disrupting nucleic acid synthesis and inducing apoptosis in rapidly proliferating cells.
Benefits and Advantages
Used in cancer‑cytotoxicity assays, TS‑inhibition research, RNA‑interference modelling and chemotherapeutic sensitivity studies.
Side Effects and Risks
Myelosuppression, mucositis, cardiotoxicity, neurotoxicity and dermatologic reactions.
Datasheet
| Molecular Formula | C4H3FN2O2 |
|---|---|
| Molecular Weight | 130.08 g/mol |
| CAS Number | 51-21-8 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | 5-Fluorouracil; fluorouracil; 51-21-8; Efudex; Fluracil |
| IUPAC/Chemical Name | 5-fluoro-1H-pyrimidine-2,4-dione |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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