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Product Description
Mechanism of Action
Etofylline nicotinate combines etofylline with nicotinic acid, providing bronchodilation alongside enhanced microcirculatory perfusion. Nicotinate‑mediated vasodilation complements the PDE‑inhibitory effect of etofylline.
Benefits and Advantages
Used in microcirculation research, combined vasodilator–bronchodilator modelling, PDE‑inhibition assays, and peripheral‑vascular pharmacology.
Side Effects and Risks
Risks include flushing, tachycardia, GI discomfort and rare hepatotoxicity. Handle with vasodilatory‑xanthine precautions.
Datasheet
| Molecular Formula | C15H15N5O4 |
|---|---|
| Molecular Weight | 329.31 g/mol |
| CAS Number | 13425-39-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Etofylline nicotinate; 13425-39-3; SN6D1V68DL; DTXSID30158609; RefChem:1068692 |
| IUPAC/Chemical Name | 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl pyridine-3-carboxylate |
| InChl Key | ZWIAODBBEZGVPY-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H15N5O4/c1-18-12-11(13(21)19(2)15(18)23)20(9-17-12)6-7-24-14(22)10-4-3-5-16-8-10/h3-5,8-9H,6-7H2,1-2H3 |
| References |
3D Conformer.
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