About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Estrone (E1) is a naturally occurring estrogen that interconverts with estradiol via 17hydroxysteroid dehydrogenases. It acts as a reservoir hormone and binds estrogen receptors to regulate reproductive and metabolic genes.
Benefits and Advantages
Used in estrogenmetabolism studies, ERligand profiling, endocrineaxis modelling, and steroidinterconversion research.
Side Effects and Risks
Risks include thromboembolism, hepatic effects, breast tenderness and hormonal imbalance. Handle with estrogensteroid precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H22O2 |
|---|---|
| Molecular Weight | 270.4 g/mol |
| CAS Number | 53-16-7 |
| Storage Condition | Store in the original package. Do not store above 25 °C. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | estrone; 53-16-7; folliculin; Theelin; estrovarin |
| IUPAC/Chemical Name | (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one |
| InChl Key | DNXHEGUUPJUMQT-CBZIJGRNSA-N |
| InChl Code | InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1 |
| References |
3D Conformer.
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