ESMOLOL HCL

Esmolol HCl is an ultrashort‑acting β1‑blocker reducing heart rate and blood pressure, used in arrhythmias. Side effects include hypotension, dizziness, and fatigue.

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Product Description


Mechanism of Action

Esmolol is an ultra–short‑acting, β₁‑selective adrenergic receptor blocker metabolized rapidly by red‑cell esterases. It decreases heart rate, AV‑node conduction and myocardial oxygen demand with minimal β₂ effects.

Benefits and Advantages

Used in cardiovascular‑dynamics modelling, β₁‑selectivity assays, arrhythmia research, and acute hemodynamic‑response simulations.

Side Effects and Risks

Risks include hypotension, bradycardia, heart block and bronchospasm (rare at high doses). Handle with cardioselective β‑blocker precautions.

Datasheet


Molecular Formula

C16H25NO4·HCl

Molecular Weight

331.8 g/mol

CAS Number

81161-17-3

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Esmolol hydrochloride; 81161-17-3; Esmolol HCL; Brevibloc; ASL-8052

IUPAC/Chemical Name

methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate;hydrochloride

InChl Key

GEKNCWBANDDJJL-UHFFFAOYSA-N

InChl Code

InChI=1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H

References

https://pubchem.ncbi.nlm.nih.gov/compound/104769;

3D Conformer.

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