About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Erythropoietin (EPO) is a glycoprotein hormone that binds the erythropoietin receptor (EPOR) on erythroid progenitor cells, activating JAK2STAT5 signalling and promoting survival, proliferation and differentiation into mature red blood cells. It also influences iron metabolism, angiogenesis and cellular hypoxia responses.
Benefits and Advantages
Used in hematopoiesismodelling studies, hypoxiasignalling research, EPORpathway assays, biomanufacturing of recombinant proteins and erythroidlineage development work.
Side Effects and Risks
Risks include hypertension, thrombosis, pure redcell aplasia (rare), flulike symptoms and increased blood viscosity. Handle with growthfactor hormone precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C42H73NO16 |
|---|---|
| Molecular Weight | 848.0 g/mol |
| CAS Number | 113427-24-0 |
| Storage Condition | Commercially available epoetin alfa injection should be refrigerated at 2-8 °C and should not be frozen. Exposure to light for periods less than 24 hours reportedly does not affect the color, clarity, or potency of the injection. … When stored as directed, commercially available preservative-free or preserved epoetin alfa injection has an expiration date of 2 or 3 years, respectively, following the date of manufacture. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | EPOETIN ALFA; Epoetin alpha; 113427-24-0; Epoetina alfa; binocrit |
| IUPAC/Chemical Name | (4R,5S,6S,7R,9R,10R,11E,13E,16R)-10-[(2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-6-[(2S,3R,4R,5S,6R)-5-[(2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-7-(2-hydroxyethyl)-5-methoxy-9,16-dimethyl-1-oxacyclohexadeca-11,13-dien-2-one |
| InChl Key | CJKGNDLRMLFWEX-IUJNAFBCSA-N |
| InChl Code | InChI=1S/C42H73NO16/c1-22-18-27(16-17-44)36(59-40-34(47)33(43(8)9)35(24(3)56-40)58-32-21-42(7,51)39(49)26(5)55-32)37(52-10)28(45)19-30(46)53-23(2)14-12-11-13-15-29(22)57-31-20-41(6,50)38(48)25(4)54-31/h11-13,15,22-29,31-40,44-45,47-51H,14,16-21H2,1-10H3/b12-11+,15-13+/t22-,23-,24-,25+,26+,27+,28-,29+,31+,32+,33-,34-,35-,36+,37+,38+,39+,40+,41-,42-/m1/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
