ERYTHROMYCIN THIOCYANATE
Erythromycin thiocyanate is a macrolide salt form with antimicrobial activity against grampositive organisms. Side effects include GI irritation, allergic reactions, and mild abdominal pain. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Erythromycin thiocyanate is a salt form providing improved stability and occasionally enhanced antimicrobial potency. Mechanism remains binding to 50S ribosomal exit tunnel to inhibit bacterial protein synthesis.
Benefits and Advantages
Used in saltform comparison research, macrolidestability studies, ribosomalaffinity assays, and antimicrobialactivity profiling.
Side Effects and Risks
Risks include GI symptoms, liverenzyme alterations and rare cardiotoxicity. Handle with macrolidesalt safety procedures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C38H68N2O13S |
|---|---|
| Molecular Weight | 793.0 g/mol |
| CAS Number | 7704-67-8 |
| Storage Condition | Commercially available erythromycin topical solutions and gels should be stored at 15 – 30 °C; exposure to heat or open flames should be avoided. The topical ointment should be stored at a temperature less than 27 °C. |
| Solubility | Soluble in water at 2mg/ml |
| Purity | Purity information is available upon request (COA). |
| Synonym | Erythromycin thiocyanate; 7704-67-8; Erythromycin, thiocyanate (salt); ERYTROVET; Y7A95YRI88 |
| IUPAC/Chemical Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;thiocyanic acid |
| InChl Key | WVRRTEYLDPNZHR-YZPBMOCRSA-N |
| InChl Code | InChI=1S/C37H67NO13.CHNS/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;2-1-3/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3H/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1 |
| References |
3D Conformer.
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