ERYTHROMYCIN SUCCINATE
Erythromycin succinate is a more stable and better‑absorbed macrolide prodrug used for various bacterial infections. Side effects include GI upset, diarrhea, and rash.
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Product Description
Mechanism of Action
Erythromycin succinate is an acid‑stable ester used primarily for parenteral formulations. After hydrolysis, active erythromycin inhibits bacterial protein synthesis at the 50S ribosome.
Benefits and Advantages
Used in injectable‑antibiotic research, macrolide PK/PD modelling, ester‑activation studies, and systemic‑delivery optimization.
Side Effects and Risks
Risks include injection‑site pain, reversible hepatotoxicity, arrhythmias and allergic reactions. Handle with succinate‑ester precautions.
Datasheet
| Molecular Formula | C41H71NO16 |
|---|---|
| Molecular Weight | 834.0 g/mol |
| CAS Number | 10605-34-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Erythromycin succinate; UNII-831SF5M65L; Erythromycin, succinate (1:1) (Salt); 831SF5M65L; Erythromycin, butanedioate (1:1) (Salt) |
| IUPAC/Chemical Name | 4-[(2S,3R,4S,6R)-4-(dimethylamino)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl]oxy-4-oxobutanoic acid |
| InChl Key | HUKYDKSXFKBBIW-DTOMAXNRSA-N |
| InChl Code | InChI=1S/C41H71NO16/c1-14-27-41(10,51)34(47)22(4)31(46)20(2)18-39(8,50)36(58-38-33(56-29(45)16-15-28(43)44)26(42(11)12)17-21(3)53-38)23(5)32(24(6)37(49)55-27)57-30-19-40(9,52-13)35(48)25(7)54-30/h20-27,30,32-36,38,47-48,50-51H,14-19H2,1-13H3,(H,43,44)/t20-,21-,22+,23+,24-,25+,26+,27-,30+,32+,33-,34-,35+,36-,38+,39-,40-,41-/m1/s1 |
| References |
3D Conformer.
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