EPITHIAZIADE
Epithiaziade is a thiazide-like diuretic increasing renal sodium and water excretion to reduce blood pressure. Side effects include electrolyte imbalance, dizziness, and increased uric acid.
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Product Description
Mechanism of Action
Epithiazide is a thiazide‑like diuretic that inhibits the Na⁺/Cl⁻ cotransporter (NCC) in the distal convoluted tubule. This reduces sodium reabsorption, increases diuresis, lowers plasma volume and decreases peripheral resistance over time.
Benefits and Advantages
Used in renal‑tubular transport research, hypertension‑model assays, electrolyte‑regulation studies, and diuretic SAR analysis.
Side Effects and Risks
Risks include hypokalemia, hyponatremia, hyperuricemia, hypercalcemia and glucose intolerance. Handle with diuretic‑class precautions.
Datasheet
| Molecular Formula | C9H12ClN3O4S2 |
|---|---|
| Molecular Weight | 309.8 g/mol |
| CAS Number | 2683-75-4 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | 6-chloro-3-propyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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