About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Enocitabine is a nucleoside analog structurally related to cytarabine. It is phosphorylated intracellularly to active triphosphates that inhibit DNA polymerase and terminate DNA chain elongation, impairing replication in rapidly dividing cells.
Benefits and Advantages
Used in nucleoside‑analog research, DNA‑polymerase inhibition assays, leukemia model systems, and cytotoxic‑antimetabolite pathway studies.
Side Effects and Risks
Risks include myelosuppression, GI toxicity, hepatotoxicity and neurotoxicity at high exposure. Handle with cytotoxic‑nucleoside precautions.
Datasheet
| Molecular Formula | C8H11N3O4 |
|---|---|
| Molecular Weight | 565.8 g/mol |
| CAS Number | 55726-47-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | enocitabine; 55726-47-1; Sunrabin; Enocitabina; Enocitabinum |
| IUPAC/Chemical Name | N-[1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]docosanamide |
| InChl Key | SAMRUMKYXPVKPA-VFKOLLTISA-N |
| InChl Code | InChI=1S/C31H55N3O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-27(36)32-26-22-23-34(31(39)33-26)30-29(38)28(37)25(24-35)40-30/h22-23,25,28-30,35,37-38H,2-21,24H2,1H3,(H,32,33,36,39)/t25-,28-,29+,30-/m1/s1 |
| References |
3D Conformer.
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