About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Dydrogesterone is a highly selective retro‑steroid progestogen structurally related to natural progesterone. It binds progesterone receptors (PR‑A and PR‑B) and promotes endometrial transformation, luteal‑phase stability and modulation of reproductive‑immune signalling.
Benefits and Advantages
Used in reproductive‑physiology studies, progesterone‑receptor modelling, luteal‑support research, and steroid‑hormone SAR analysis.
Side Effects and Risks
Risks include breast tenderness, headaches, mood changes, thromboembolic risk (low relative to other progestogens) and mild hepatic effects. Handle with hormone‑modulator precautions.
Datasheet
| Molecular Formula | C21H28O2 |
|---|---|
| Molecular Weight | 312.4 g/mol |
| CAS Number | 152-62-5 |
| Storage Condition | Do not store above 30 °C. |
| Solubility | Soluble in acetone, chloroform (1 in 2), ethanol (1 in 40) and diethyl ether (1 in 200); slightly soluble in fixed oils; sparingly soluble in methanol. |
| Purity | Purity information is available upon request (COA). |
| Synonym | dydrogesterone; 152-62-5; Isopregnenone; Hydrogesterone; Duphaston |
| IUPAC/Chemical Name | (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one |
| InChl Key | JGMOKGBVKVMRFX-HQZYFCCVSA-N |
| InChl Code | InChI=1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4-5,12,16-19H,6-11H2,1-3H3/t16-,17+,18-,19+,20+,21+/m0/s1 |
| References |
3D Conformer.
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