DYCLONINE

Dyclonine is a topical anesthetic blocking sodium channels to reduce throat and mucosal pain. Side effects include numbness, mild irritation, and rare allergic reactions. Only GMP materials will be supplied, logistics all according to GDP.

SKU: c88546556072 Category: Tag:

Product Description


Mechanism of Action

Dyclonine is a topical anesthetic that blocks voltagegated sodium channels in sensory neurons, inhibiting depolarization and preventing actionpotential propagation. It provides localized analgesia without structural relation to amide or ester anesthetics.

Benefits and Advantages

Used in sodiumchannel pharmacology, peripheralnerve blockade studies, topical anesthetic SAR research, and sensorynerve conduction modelling.

Side Effects and Risks

Risks include mucosal irritation, numbness, hypersensitivity, CNS excitation at high doses and methemoglobinemia (rare). Handle with localanesthetic precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C18H27NO2

Molecular Weight

289.4 g/mol

CAS Number

586-60-7

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Soluble (HCl salt)

Purity

Purity information is available upon request (COA).

Synonym

dyclonine; Dyclocaine; 586-60-7; Diclonina; Dycloninum

IUPAC/Chemical Name

1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one

InChl Key

BZEWSEKUUPWQDQ-UHFFFAOYSA-N

InChl Code

InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3

References

https://pubchem.ncbi.nlm.nih.gov/compound/3180;

3D Conformer.

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