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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Doxofylline is a xanthine derivative with bronchodilatory activity but reduced adenosine‑receptor antagonism compared to theophylline. It inhibits phosphodiesterase, increasing intracellular cAMP and promoting smooth‑muscle relaxation with fewer CNS and cardiac side effects than classical xanthines.
Benefits and Advantages
Used in bronchodilation‑mechanism modelling, PDE‑inhibition assays, airway‑hyperreactivity research, and xanthine‑SAR pharmacology.
Side Effects and Risks
Risks include nausea, tremor, mild tachycardia, insomnia and rare arrhythmias. Handle with xanthine‑bronchodilator precautions.
Datasheet
| Molecular Formula | C11H14N4O4 |
|---|---|
| Molecular Weight | 266.25 g/mol |
| CAS Number | 69975-86-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | DOXOFYLLINE; 69975-86-6; Doxophylline; Dioxyfilline; Ansimar |
| IUPAC/Chemical Name | 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione |
| InChl Key | HWXIGFIVGWUZAO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3 |
| References |
3D Conformer.
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