DISAMIDE

Disamide is an antiarrhythmic affecting cardiac ion channels. Benefits include stabilized cardiac rhythm. Side effects may include dizziness or conduction abnormalities. Only GMP materials will be supplied, logistics all according to GDP.

SKU: e1c82e5206b4 Category: Tag:

Product Description


Mechanism of Action

Disamide is a classI antiarrhythmic agent structurally related to other sodiumchannel blockers. It inhibits fast voltagegated Na⁺ channels in cardiac tissue, decreasing phase0 depolarization, slowing conduction velocity, and stabilizing myocardial excitability. This can suppress certain tachyarrhythmias by reducing ectopic automaticity.

Benefits and Advantages

Used in cardiac electrophysiology research, Nachannel pharmacology, arrhythmiamodel development, and antiarrhythmic drug SAR studies.

Side Effects and Risks

Risks include proarrhythmia (QRS or QT changes), hypotension, negative inotropy, dizziness and GI upset. Handle with cardioactivedrug precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C7H9ClN2O4S2

Molecular Weight

284.7 g/mol

CAS Number

671-88-5

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Disulfamide; Disulphamide; 671-88-5; 5-Chlorotoluene-2,4-disulfonamide; 4-Chloro-6-methyl-1,3-benzenedisulfonamide

IUPAC/Chemical Name

4-chloro-6-methylbenzene-1,3-disulfonamide

InChl Key

RCFKEIREOSXLET-UHFFFAOYSA-N

InChl Code

InChI=1S/C7H9ClN2O4S2/c1-4-2-5(8)7(16(10,13)14)3-6(4)15(9,11)12/h2-3H,1H3,(H2,9,11,12)(H2,10,13,14)

References

https://pubchem.ncbi.nlm.nih.gov/compound/68935;

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