DIPYRIDAMOL
Dipyridamole inhibits adenosine uptake and platelet aggregation, improving coronary blood flow. Used in cardiac stress testing. Side effects include headache, flushing, and dizziness. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dipyridamole is a phosphodiesterase inhibitor and adenosineuptake blocker that increases intracellular cAMP in platelets and vascular smooth muscle. It enhances endogenous adenosine levels by blocking reuptake and metabolism, leading to vasodilation and inhibition of platelet aggregation via AA receptor activation and cAMP elevation.
Benefits and Advantages
Used in plateletfunction research, vasodilationpathway modelling, adenosinesignalling studies, stresstesting pharmacology and antithromboticmechanism investigations.
Side Effects and Risks
Risks include headache, flushing, hypotension, dizziness, GI upset and, rarely, bleeding when combined with other antithrombotics. Handle with vasodilator/antiplatelet precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C24H40N8O4 |
|---|---|
| Molecular Weight | 504.6 g/mol |
| CAS Number | 58-32-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Slightly |
| Purity | Purity information is available upon request (COA). |
| Synonym | dipyridamole; 58-32-2; Persantin; Dipyridamine; Persantine |
| IUPAC/Chemical Name | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol |
| InChl Key | IZEKFCXSFNUWAM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2 |
| References |
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