DIPYRIDAMOL

Dipyridamole inhibits adenosine uptake and platelet aggregation, improving coronary blood flow. Used in cardiac stress testing. Side effects include headache, flushing, and dizziness. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 37c6af7c9c9c Category: Tag:

Product Description


Mechanism of Action

Dipyridamole is a phosphodiesterase inhibitor and adenosineuptake blocker that increases intracellular cAMP in platelets and vascular smooth muscle. It enhances endogenous adenosine levels by blocking reuptake and metabolism, leading to vasodilation and inhibition of platelet aggregation via AA receptor activation and cAMP elevation.

Benefits and Advantages

Used in plateletfunction research, vasodilationpathway modelling, adenosinesignalling studies, stresstesting pharmacology and antithromboticmechanism investigations.

Side Effects and Risks

Risks include headache, flushing, hypotension, dizziness, GI upset and, rarely, bleeding when combined with other antithrombotics. Handle with vasodilator/antiplatelet precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C24H40N8O4

Molecular Weight

504.6 g/mol

CAS Number

58-32-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Slightly

Purity

Purity information is available upon request (COA).

Synonym

dipyridamole; 58-32-2; Persantin; Dipyridamine; Persantine

IUPAC/Chemical Name

2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol

InChl Key

IZEKFCXSFNUWAM-UHFFFAOYSA-N

InChl Code

InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/3108;

3D Conformer.

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