About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Diphenylcyclopropenone (DPCP) is a potent topical contact sensitizer that induces a type IV (delayed) hypersensitivity reaction. It forms haptenprotein complexes in the skin, which are processed by antigenpresenting cells and presented to Tlymphocytes, triggering a robust cellmediated immune response. This controlled immune activation can redirect autoimmune and inflammatory activity within the hair follicle microenvironment.
Benefits and Advantages
Used in alopecia areata research, contacthypersensitivity modelling, cutaneous immunology studies, Tcell activation assays, and topical immunotherapy mechanism investigations.
Side Effects and Risks
Risks include severe local dermatitis, blistering, hyperpigmentation or hypopigmentation, lymphadenopathy and rare systemic reactions. Handle with strong sensitizer precautions and appropriate dermal protection.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C15H10O |
|---|---|
| Molecular Weight | 210.24 g/mol |
| CAS Number | 886-38-4 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | Diphenylcyclopropenone; 886-38-4; Diphencyprone; 2,3-Diphenylcycloprop-2-en-1-one; 2,3-Diphenylcyclopropenone |
| IUPAC/Chemical Name | 1,2-diphenylcycloprop-2-en-1-one |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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