DIOXIDIN
Dioxidin is a broad-spectrum antimicrobial disrupting bacterial DNA. Used topically or in severe infections. Side effects include irritation, nephrotoxicity, and potential mutagenicity.
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Product Description
Mechanism of Action
Dioxidin (dioxidine) is a broad‑spectrum antimicrobial with activity against gram‑negative and some gram‑positive organisms. Its mechanism involves interference with bacterial DNA synthesis, formation of intracellular free radicals, and disruption of membrane integrity.
Benefits and Advantages
Used in antimicrobial‑resistance modelling, DNA‑damage pathway research, ROS‑generation studies, and bactericidal mechanism analysis.
Side Effects and Risks
Risks include nephrotoxicity, local irritation (topical), mutagenicity concerns in high‑dose models, and systemic toxicity with prolonged exposure. Handle with cytotoxic‑antimicrobial precautions.
Datasheet
| Molecular Formula | C10H10N2O4 |
|---|---|
| Molecular Weight | 222.20 g/mol |
| CAS Number | 17311-31-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | DIOXIDINE; 17311-31-8; Dioxydine; Dioxidin; 2,3-Quinoxalinedimethanol, 1,4-dioxide |
| IUPAC/Chemical Name | [3-(hydroxymethyl)-1-oxido-4-oxoquinoxalin-4-ium-2-yl]methanol |
| InChl Key | DOIGHQCAQBRSKI-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H10N2O4/c13-5-9-10(6-14)12(16)8-4-2-1-3-7(8)11(9)15/h1-4,13-14H,5-6H2 |
| References |
3D Conformer.
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