DICLOXACILLIN SODIUM

Dicloxacillin sodium is a lactam antibiotic effective against penicillinaseproducing staphylococci. Side effects include diarrhea, rash, and allergic reactions. Only GMP materials will be supplied, logistics all according to GDP.

SKU: d30ca7ef8e5c Category: Tag:

Product Description


Mechanism of Action

Dicloxacillin sodium is a semisynthetic isoxazolyl penicillin that inhibits bacterial cellwall crosslinking by irreversibly binding PBPs. Its steric configuration confers resistance to staphylococcal lactamases. It is highly active against MSSA and other grampositive organisms.

Benefits and Advantages

Used in penicillinderivative SAR studies, grampositive antimicrobial modelling, lactamaseresistance research, and PBPcomplexformation assays.

Side Effects and Risks

Risks include allergic reactions (including anaphylaxis), hepatotoxicity, diarrhea, and rare interstitial nephritis. Handle under lactam antibiotic containment protocols.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C19H16Cl2N3NaO5S

Molecular Weight

492.3 g/mol

CAS Number

343-55-5

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Dicloxacillin sodium; 343-55-5; Sodium dicloxacillin; Pathocil; Dycill

IUPAC/Chemical Name

sodium (2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChl Key

GXOMMGAFBINOJY-SLINCCQESA-M

InChl Code

InChI=1S/C19H17Cl2N3O5S.Na/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);/q;+1/p-1/t13-,14+,17-;/m1./s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/23667628;

3D Conformer.

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