DESMOPRESSIN
Desmopressin is a vasopressin analogue that increases renal water reabsorption via V2 receptors, treating diabetes insipidus and nocturnal enuresis. Side effects include hyponatremia, headache, and mild edema. Only GMP materials will be supplied, logistics all according to GDP.
About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Desmopressin (DDAVP) is a selective vasopressin Vreceptor agonist that enhances renal water reabsorption by increasing aquaporin2 insertion in renal collecting ducts. It also stimulates release of von Willebrand factor and factor VIII from endothelial storage sites, improving hemostasis.
Benefits and Advantages
Used in renalwater transport research, vasopressinpathway modelling, coagulation studies, diabetesinsipidus models, and endocrinehormone signalling investigations.
Side Effects and Risks
Risks include hyponatremia, seizures (secondary to low sodium), edema, headache and rare thrombotic events. Handle with hormoneanalogue precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C46H64N14O12S2 |
|---|---|
| Molecular Weight | 1069.2 g/mol |
| CAS Number | 16679-58-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | DESMOPRESSIN; 16679-58-6; Desmopresina; Desmopressine; Desmopressinum |
| IUPAC/Chemical Name | (2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide |
| InChl Key | NFLWUMRGJYTJIN-PNIOQBSNSA-N |
| InChl Code | InChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

