DESMOPRESSIN

Desmopressin is a vasopressin analogue that increases renal water reabsorption via V2 receptors, treating diabetes insipidus and nocturnal enuresis. Side effects include hyponatremia, headache, and mild edema. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 1cdaf8c00f91 Category: Tag:

Product Description


Mechanism of Action

Desmopressin (DDAVP) is a selective vasopressin Vreceptor agonist that enhances renal water reabsorption by increasing aquaporin2 insertion in renal collecting ducts. It also stimulates release of von Willebrand factor and factor VIII from endothelial storage sites, improving hemostasis.

Benefits and Advantages

Used in renalwater transport research, vasopressinpathway modelling, coagulation studies, diabetesinsipidus models, and endocrinehormone signalling investigations.

Side Effects and Risks

Risks include hyponatremia, seizures (secondary to low sodium), edema, headache and rare thrombotic events. Handle with hormoneanalogue precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C46H64N14O12S2

Molecular Weight

1069.2 g/mol

CAS Number

16679-58-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

DESMOPRESSIN; 16679-58-6; Desmopresina; Desmopressine; Desmopressinum

IUPAC/Chemical Name

(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide

InChl Key

NFLWUMRGJYTJIN-PNIOQBSNSA-N

InChl Code

InChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/5311065;

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download