DEHYDROCORTISONE ACETATE
Delamanid is a nitroimidazole derivative that inhibits mycolic acid synthesis in Mycobacterium tuberculosis. It is used in multidrugresistant TB regimens. Benefits include improved culture conversion when combined with other agents. Side effects include QT prolongation, nausea, and headache. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dehydrocortisone acetate is a corticosteroid derivative with reduced glucocorticoid potency. It acts through classic GRmediated gene regulation, decreasing inflammatory cytokines, inhibiting arachidonicacid pathways, and modulating carbohydrate metabolism.
Benefits and Advantages
Used in steroidpathway modelling, GRactivation assays, inflammationsuppression studies, and corticosteroid SAR research.
Side Effects and Risks
Risks include mild adrenal suppression, metabolic imbalance, fluid retention and skin thinning (topical). Handle with glucocorticoidclass precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C23H30O5 |
|---|---|
| Molecular Weight | 386.48 g/mol |
| CAS Number | 53-03-2 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | methanol; methyl alcohol; 67-56-1; wood alcohol; Wood naphtha |
| IUPAC/Chemical Name | [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-10,13-dimethyl-3,20-dioxopregna-1,4-dien-17-yl] acetate |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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