CYCLODEXTRIN

Cyclocytidine is a nucleoside analogue interfering with DNA replication, used experimentally and for antiviral studies. Side effects may include cytotoxicity, nausea, and bone marrow suppression. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 6001e00748b8 Category: Tag:

Product Description


Mechanism of Action

Cyclodextrins are cyclic oligosaccharides that form inclusion complexes with hydrophobic molecules. Their hydrophobic cavity and hydrophilic exterior allow them to improve solubility, stability and delivery of poorly soluble compounds. They modulate molecular binding through hostguest interactions.

Benefits and Advantages

Used in drugdelivery research, solubilityenhancement studies, hostguest chemistry modelling, toxinbinding assays and pharmaceuticalexcipient development.

Side Effects and Risks

Risks include GI discomfort, nephrotoxicity at high doses (certain derivatives) and extraction of cholesterol from membranes. Handle with excipientclass precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C36H60O30

Molecular Weight

972.8 g/mol

CAS Number

12619-70-4

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Cyclodextrin; Cycloamylose; Cyclodextrins; Cyclomaltooligosaccharides; Celdex

IUPAC/Chemical Name

5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol

InChl Key

HFHDHCJBZVLPGP-UHFFFAOYSA-N

InChl Code

InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/320760;

3D Conformer.

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