About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Coumarin is a benzopyrone compound with anticoagulantrelated structural properties, though the parent compound itself does not strongly inhibit vitaminK recycling. It modulates cytochrome P450 enzymes, exhibits antioxidant activity, and influences inflammatory and calciumsignalling pathways. It is also a precursor for numerous pharmacologically active derivatives.
Benefits and Advantages
Used in flavonoid/coumarin SAR research, cytochromemodulation assays, phototoxicity studies, naturalproduct biosynthesis modelling, and anticoagulantderivative development.
Side Effects and Risks
Risks include hepatotoxicity at high doses, photosensitivity, enzymeinteraction effects and allergenic potential. Handle with naturalproduct compound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C9H6O2 |
|---|---|
| Molecular Weight | 146.14 g/mol |
| CAS Number | 91-64-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | less than 0.1 mg/mL at 63.5 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | coumarin; 91-64-5; 2H-Chromen-2-one; 2H-1-Benzopyran-2-one; cumarin |
| IUPAC/Chemical Name | chromen-2-one |
| InChl Key | ZYGHJZDHTFUPRJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H |
| References |
3D Conformer.
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