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Product Description
Mechanism of Action
Cloxyquine is a halogenated quinoline derivative with broad antiparasitic and antimicrobial properties. Its mechanism involves interference with nucleic‑acid synthesis, disruption of protozoal membrane integrity, and chelation of metal ions essential for microbial enzymatic activity. Its lipophilic structure enables accumulation within parasitic vacuoles, enhancing intracellular antimicrobial action.
Benefits and Advantages
Used in protozoal‑model research, quinoline‑SAR studies, helminth‑pathway investigations, intracellular penetration assays, and evaluation of metal‑chelation antimicrobial mechanisms.
Side Effects and Risks
Risks include hepatotoxicity, GI irritation, neurotoxicity, hypersensitivity and retinal disturbances (class‑related quinoline effects). Handle with antiparasitic‑compound precautions.
Datasheet
| Molecular Formula | C9H6ClNO |
|---|---|
| Molecular Weight | 179.60 g/mol |
| CAS Number | 130-16-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 5-CHLORO-8-HYDROXYQUINOLINE; 130-16-5; 5-Chloroquinolin-8-ol; cloxyquin; Cloxiquine |
| IUPAC/Chemical Name | 5-chloroquinolin-8-ol |
| InChl Key | CTQMJYWDVABFRZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H |
| References |
3D Conformer.
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