CLOXACILLIN SODIUM
Cloxacillin sodium is a β-lactam antibiotic effective against penicillinase-producing staphylococci. Side effects include allergic reactions, nausea, and diarrhea.
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Product Description
Mechanism of Action
Cloxacillin sodium is the rapidly absorbed salt form of cloxacillin. Mechanism identical: inhibition of bacterial cell‑wall crosslinking through PBP binding, resistant to penicillinase‑producing *Staphylococcus* strains.
Benefits and Advantages
Used in gram‑positive susceptibility studies, β‑lactamase‑resistant antibiotic modelling, PBP‑affinity assays and staphylococcal‑infection research.
Side Effects and Risks
Risks include allergic reactions, hepatic injury, GI discomfort and rare blood‑dyscrasias. Handle following β‑lactam handling protocols.
Datasheet
| Molecular Formula | C19H17ClN3NaO5S |
|---|---|
| Molecular Weight | 457.9 g/mol |
| CAS Number | 642-78-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cloxacillin sodium; 642-78-4; Sodium cloxacillin; Cloxacillin sodium anhydrous; Monosodium cloxacillin |
| IUPAC/Chemical Name | sodium (2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| InChl Key | SCLZRKVZRBKZCR-SLINCCQESA-M |
| InChl Code | InChI=1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1 |
| References |
3D Conformer.
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