About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Clofibrate is a fibrateclass lipid regulator that activates PPAR, increasing fattyacid oxidation and reducing serum triglycerides. It enhances lipoproteinlipase activity and modulates hepatic lipid metabolism.
Benefits and Advantages
Used in lipidmetabolism research, fibrate SAR studies, triglyceridelowering modelling, hepaticgene expression assays and PPARtargeted drug development.
Side Effects and Risks
Risks include gallstone formation, hepatotoxicity, myopathy and GI upset. Handle with lipidactive agent precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C12H15ClO3 |
|---|---|
| Molecular Weight | 242.70 g/mol |
| CAS Number | 637-07-0 |
| Storage Condition | Clofibrate liquid-filled capsules should be stored in well-closed, light-resistant containers, @ a temp less than 40 °C. preferably @ 15-30 °C; freezing of the liquid-filled capsules should be avoided. |
| Solubility | Insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | clofibrate; 637-07-0; Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate; Ethyl clofibrate; Atromid-S |
| IUPAC/Chemical Name | ethyl 2-(4-chlorophenoxy)-2-methylpropanoate |
| InChl Key | KNHUKKLJHYUCFP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3 |
| References |
3D Conformer.
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