CLOFIBRATE ALUMINIUM
Clofibrate aluminum has similar lipidlowering properties with altered pharmacokinetics. Side effects include nausea and rare hepatotoxicity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Clofibrate aluminium is a lesssoluble complex of clofibrate providing modified release and altered absorption properties. Mechanism identical: PPAR activation leading to triglyceride reduction and improved lipid transport.
Benefits and Advantages
Used in formulationrelease profiling, saltform pharmacokinetics, lipidregulation modelling and PPAR signalling research.
Side Effects and Risks
Risks are similar to clofibrate but with potential aluminiumrelated GI effects. Handle as a metalassociated fibrate compound.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C12H15ClO3·Al |
|---|---|
| Molecular Weight | 290.5 g/mol |
| CAS Number | 637-07-0 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | clofibrate; 637-07-0; Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate; Ethyl clofibrate; Atromid-S |
| IUPAC/Chemical Name | 2-(4-chlorophenoxy)-2-methylpropanoate aluminium salt |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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