CIPROFIBRATE

Ciprofibrate activates PPAR‑α to reduce triglycerides and improve HDL levels. Side effects include muscle pain, GI upset, and liver enzyme elevation.

SKU: 1d1a20148c59 Category: Tag:

Product Description


Mechanism of Action

Ciprofibrate is a fibrate‑class hypolipidemic agent that activates peroxisome proliferator‑activated receptor‑alpha (PPAR‑α). Activation increases β‑oxidation of fatty acids, enhances lipoprotein‑lipase activity and decreases serum triglycerides while modestly improving HDL levels. It regulates genes controlling lipid metabolism and inflammation.

Benefits and Advantages

Used in PPAR‑α signalling research, lipid‑metabolism studies, triglyceride‑lowering pathway modelling, hepatic fatty‑acid oxidation research and fibrate SAR analysis.

Side Effects and Risks

Risks include hepatotoxicity, myopathy (higher risk with statins), gallstones, GI symptoms and elevated liver enzymes. Handle with lipid‑modulating compound precautions.

Datasheet


Molecular Formula

C13H14Cl2O3

Molecular Weight

289.15 g/mol

CAS Number

52214-84-3

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Ciprofibrate; 52214-84-3; 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid; Ciprofibratum; Ciprofibrato

IUPAC/Chemical Name

2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

InChl Key

KPSRODZRAIWAKH-UHFFFAOYSA-N

InChl Code

InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

References

https://pubchem.ncbi.nlm.nih.gov/compound/2763;

3D Conformer.

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