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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cinnarizine is a calciumchannel blocker with antihistaminic (H) and antivertigo properties. It inhibits Ltype calcium channels, reducing smoothmuscle contractility, while its Hantagonism suppresses vestibular nuclei excitabilityuseful in motionsickness research. It also improves microcirculation by reducing blood viscosity.
Benefits and Advantages
Used in vestibularfunction studies, motionsickness modelling, calciumchannel pharmacology, cerebralperfusion research and combined antihistaminevasodilator SAR investigations.
Side Effects and Risks
Risks include sedation, weight gain, extrapyramidal symptoms (rare), dry mouth and hypotension. Handle with CNSactive calciumantagonist precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C26H28N2 |
|---|---|
| Molecular Weight | 368.5 g/mol |
| CAS Number | 298-57-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 1.72e-03 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | cinnarizine; 298-57-7; Stugeron; Dimitron; Folcodal |
| IUPAC/Chemical Name | 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine |
| InChl Key | DERZBLKQOCDDDZ-JLHYYAGUSA-N |
| InChl Code | InChI=1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+ |
| References |
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