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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Product Description
Mechanism of Action
Cinchocaine (dibucaine) is a potent amide‑type local anaesthetic that inhibits voltage‑gated sodium channels (Nav), stabilising the inactivated channel state and blocking neuronal action‑potential propagation. It produces long‑acting anaesthesia due to high lipid solubility and strong protein binding.
Benefits and Advantages
Used in sodium‑channel pharmacology studies, local‑anaesthetic SAR research, nociception modelling, membrane‑partitioning assays and comparative potency profiling among long‑acting anaesthetics.
Side Effects and Risks
Risks include cardiotoxicity, neurotoxicity, methemoglobinemia (rare), CNS depression or excitation, and allergic reactions. Handle under strict local‑anaesthetic safety precautions.
Datasheet
| Molecular Formula | C20H29N3O2 |
|---|---|
| Molecular Weight | 343.5 g/mol |
| CAS Number | 85-79-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | dibucaine; Cinchocaine; 85-79-0; Nupercainal; Dermacaine |
| IUPAC/Chemical Name | 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide |
| InChl Key | PUFQVTATUTYEAL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24) |
| References |
3D Conformer.
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