CIMIGENOSIDE
Cimigenoside is a natural triterpene glycoside with anti-inflammatory and estrogenmodulating properties. Benefits may include symptom relief in menopausal discomfort. Side effects are minimal but may involve GI upset. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Cimigenoside is a triterpene glycoside found in *Cimicifuga* species with estrogenmodulating, antiinflammatory and antioxidant activity. It modulates MAPK and NF-κB pathways, influences cytokine expression and may interact with estrogen receptors indirectly. Its glycoside structure affects solubility and cellular uptake.
Benefits and Advantages
Used in phytoestrogen research, naturalproduct SAR studies, inflammatorypathway modelling, antioxidant evaluations, botanicalextract standardisation and signallingcascade experiments.
Side Effects and Risks
Risks include estrogenlike effects, hepatotoxicity (rare), GI upset and potential herbdrug interactions. Handle with botanicalcompound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C35H56O9 |
|---|---|
| Molecular Weight | 620.8 g/mol |
| CAS Number | 27994-11-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cimigenoside; Cimigenol xyloside; 1CW26VCP4H; (2S,3R,4S,5R)-2-[[(1S,2R,3S,4R,7R,9S,12R,14S,17R,18R,19R,21R,22S)-2-hydroxy-22-(2-hydroxypropan-2-yl)-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.01,18.03,17.04,14.07,12.012,14]tetracosan-9-yl]oxy]oxane-3,4,5-triol; beta-D-Xylopyranoside, (3beta,15alpha,16alpha,23R,24S)-16,23:16,24-diepoxy-15,25-dihydroxy-9,19-cyclolanostan-3-yl |
| IUPAC/Chemical Name | (2S,3R,4S,5R)-2-[[(1S,2R,3S,4R,7R,9S,12R,14S,17R,18R,19R,21R,22S)-2-hydroxy-22-(2-hydroxypropan-2-yl)-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.01,18.03,17.04,14.07,12.012,14]tetracosan-9-yl]oxy]oxane-3,4,5-triol |
| InChl Key | BTPYUWOBZFGKAI-XYGBCAHESA-N |
| InChl Code | InChI=1S/C35H56O9/c1-17-14-19-26(30(4,5)40)44-35(43-19)25(17)31(6)12-13-34-16-33(34)11-10-22(42-27-24(38)23(37)18(36)15-41-27)29(2,3)20(33)8-9-21(34)32(31,7)28(35)39/h17-28,36-40H,8-16H2,1-7H3/t17-,18-,19-,20+,21+,22+,23+,24-,25-,26+,27+,28-,31-,32-,33-,34+,35+/m1/s1 |
| References | PubChem; ChemBL; FDA; |
3D Conformer.
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