CIMIGENOSIDE

Cimigenoside is a natural triterpene glycoside with anti-inflammatory and estrogenmodulating properties. Benefits may include symptom relief in menopausal discomfort. Side effects are minimal but may involve GI upset. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of Action

Cimigenoside is a triterpene glycoside found in *Cimicifuga* species with estrogenmodulating, antiinflammatory and antioxidant activity. It modulates MAPK and NF-κB pathways, influences cytokine expression and may interact with estrogen receptors indirectly. Its glycoside structure affects solubility and cellular uptake.

Benefits and Advantages

Used in phytoestrogen research, naturalproduct SAR studies, inflammatorypathway modelling, antioxidant evaluations, botanicalextract standardisation and signallingcascade experiments.

Side Effects and Risks

Risks include estrogenlike effects, hepatotoxicity (rare), GI upset and potential herbdrug interactions. Handle with botanicalcompound precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C35H56O9

Molecular Weight

620.8 g/mol

CAS Number

27994-11-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Cimigenoside; Cimigenol xyloside; 1CW26VCP4H; (2S,3R,4S,5R)-2-[[(1S,2R,3S,4R,7R,9S,12R,14S,17R,18R,19R,21R,22S)-2-hydroxy-22-(2-hydroxypropan-2-yl)-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.01,18.03,17.04,14.07,12.012,14]tetracosan-9-yl]oxy]oxane-3,4,5-triol; beta-D-Xylopyranoside, (3beta,15alpha,16alpha,23R,24S)-16,23:16,24-diepoxy-15,25-dihydroxy-9,19-cyclolanostan-3-yl

IUPAC/Chemical Name

(2S,3R,4S,5R)-2-[[(1S,2R,3S,4R,7R,9S,12R,14S,17R,18R,19R,21R,22S)-2-hydroxy-22-(2-hydroxypropan-2-yl)-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.01,18.03,17.04,14.07,12.012,14]tetracosan-9-yl]oxy]oxane-3,4,5-triol

InChl Key

BTPYUWOBZFGKAI-XYGBCAHESA-N

InChl Code

InChI=1S/C35H56O9/c1-17-14-19-26(30(4,5)40)44-35(43-19)25(17)31(6)12-13-34-16-33(34)11-10-22(42-27-24(38)23(37)18(36)15-41-27)29(2,3)20(33)8-9-21(34)32(31,7)28(35)39/h17-28,36-40H,8-16H2,1-7H3/t17-,18-,19-,20+,21+,22+,23+,24-,25-,26+,27+,28-,31-,32-,33-,34+,35+/m1/s1

References

PubChem; ChemBL; FDA;

3D Conformer.

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