About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cimetidine hydrochloride is the stable, watersoluble salt widely used in research and clinical formulations. Mechanism identical: Hreceptor blockade on parietal cells reduces gastric acid secretion. Also notable for potent CYP inhibition affecting many drugs.
Benefits and Advantages
Used in solutionstability studies, Hreceptor pharmacology, CYP450 inhibition screening, gastricphysiology experiments and acidsuppression modelling.
Side Effects and Risks
Risks include antiandrogenic effects, hepatic dysfunction, CNS disturbances and extensive druginteraction risk. Handle with acidsecretionmodulator precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C10H17ClN6S |
|---|---|
| Molecular Weight | 288.80 g/mol |
| CAS Number | 70059-30-2 |
| Storage Condition | Preserve in tight, light resistant containers at controlled room temperatures. |
| Solubility | 5 mg/mL at 68 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cimetidine hydrochloride; 70059-30-2; Cimetidine Hcl; WF10491673; DTXSID10990302 |
| IUPAC/Chemical Name | 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine;hydrochloride |
| InChl Key | QJHCNBWLPSXHBL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H16N6S.ClH/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11;/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14);1H |
| References | PubChem; ChemBL; FDA; |
3D Conformer.
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