About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Chlorzoxazone is a centrally acting skeletal muscle relaxant that depresses polysynaptic reflex arcs in the spinal cord. It reduces excessive skeletalmuscle tone without directly affecting neuromuscular junction transmission. Its mechanism involves enhancement of inhibitory interneuron activity and modulation of GABAergic signalling.
Benefits and Advantages
Used in musclespasm modelling, CNS-depressant mechanism studies, spinalreflex research, comparative musclerelaxant pharmacology and druginteraction metabolism studies (notably CYP2E1).
Side Effects and Risks
Risks include hepatotoxicity (idiosyncratic), sedation, dizziness, GI discomfort and impaired psychomotor coordination. Handle as a CNS depressant with hepatotoxic potential.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C7H4ClNO2 |
|---|---|
| Molecular Weight | 169.56 g/mol |
| CAS Number | 95-25-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | chlorzoxazone; 95-25-0; Paraflex; 5-Chloro-2-benzoxazolone; 5-Chloro-2(3H)-benzoxazolone |
| IUPAC/Chemical Name | 5-chloro-3H-1,3-benzoxazol-2-one |
| InChl Key | TZFWDZFKRBELIQ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
