About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Chloroquine sulfate is another well-established salt form of chloroquine with enhanced solubility. Its mechanism remains identical: lysosomal accumulation, pH elevation, heme‑detoxification inhibition and interference with DNA replication indirectly through heme‑reactive oxidative damage.
Benefits and Advantages
Used in malaria‑resistance modelling, autophagy pathway inhibition research, TLR‑signalling studies, antiviral assays and lysosome‑acidification investigations. Commonly used for mechanistic comparison across chloroquine salts.
Side Effects and Risks
Risks include cardiomyopathy, retinal toxicity, myopathy, dermatologic reactions and metabolic disturbances. Handle with caution due to broad systemic toxicity.
Datasheet
| Molecular Formula | C18H28ClN3O4S |
|---|---|
| Molecular Weight | 418.0 g/mol |
| CAS Number | 132-73-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Chloroquine sulfate; Chloroquine sulphate; 132-73-0; Lariago; Nivaquine |
| IUPAC/Chemical Name | 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;sulfuric acid |
| InChl Key | OJPWHUOVKVKBQB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H26ClN3.H2O4S/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);(H2,1,2,3,4) |
| References |
3D Conformer.
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