About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Chloroquine phosphate is a widely used salt form of chloroquine providing stable aqueous solubility. It accumulates in parasite vacuoles and mammalian lysosomes, impairing hemepolymerisation, altering autophagic flux, and interfering with TLRmediated immune signalling. Also used to block viral entry via endosomal pH elevation.
Benefits and Advantages
Used in parasitemetabolism modelling, hostpathogen interaction research, autophagy and lysosomedysfunction studies, tolllike receptor pathway analysis and antiviralscreening platforms.
Side Effects and Risks
Risks include retinopathy, cardiotoxicity, neuropsychiatric effects, GI symptoms and hepatic stress. Handle with highsafety controls due to systemic toxicity.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H32ClN3O8P2 |
|---|---|
| Molecular Weight | 515.9 g/mol |
| CAS Number | 1688677-89-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Chloroquine diphosphate; Chloroquine phosphate; Arechin; Avloclor; Resochin |
| IUPAC/Chemical Name | 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoric acid |
| InChl Key | QKICWELGRMTQCR-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
