CHLOROHEMIN

Chlorohemin is a heme derivative used in biochemical research to study cytochrome activity. Side effects relate to laboratory exposure, including irritation or oxidative stress.

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Product Description


Mechanism of Action

Chlorohemin (hemin chloride) is an iron‑containing porphyrin complex mimicking the prosthetic group of hemoproteins. It modulates heme‑oxygenase‑1 (HO‑1) expression, influences oxidative‑stress responses, and participates in electron‑transfer and catalytic reactions. Chlorohemin is widely used as a biochemical reagent for studying heme‑dependent processes.

Benefits and Advantages

Used in heme‑protein research, oxidative‑stress modelling, HO‑1 pathway studies, cytochrome biochemistry, iron‑metabolism analysis, and enzyme‑catalysis assays.

Side Effects and Risks

Risks include oxidative damage, skin/eye irritation, iron overload (systemic exposure) and photosensitization. Handle with heme‑protein reagent precautions.

Datasheet


Molecular Formula

C34H32ClFeN4O4

Molecular Weight

651.9 g/mol

CAS Number

16009-13-5

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

RefChem:1093269; Npc76529; hemin; Chlorohemin; Panhematin

IUPAC/Chemical Name

3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(3+);chloride

InChl Key

BTIJJDXEELBZFS-UHFFFAOYSA-K

InChl Code

InChI=1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3

References

https://pubchem.ncbi.nlm.nih.gov/compound/455658;

3D Conformer.

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