CEPHRADINE
Cephradine is a cephalosporin with broad gram‑positive activity, used for respiratory infections. Side effects include GI upset and allergic reactions.
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Product Description
Mechanism of Action
Cephradine is a first‑generation cephalosporin structurally and mechanistically similar to cephalexin. It binds PBPs and inhibits bacterial cell‑wall peptidoglycan crosslinking, resulting in bactericidal lysis. Its chemical stability provides strong oral and parenteral bioavailability.
Benefits and Advantages
Used in gram‑positive bacteriology modelling, peptidoglycan‑synthesis studies, β‑lactam SAR comparisons, MIC profiling, and cell‑wall structure–function research.
Side Effects and Risks
Risks include allergic reactions, diarrhoea, hepatic enzyme elevation and rare haematologic disturbances. Standard β‑lactam safety protocols apply.
Datasheet
| Molecular Formula | C16H19N3O4S |
|---|---|
| Molecular Weight | 349.4 g/mol |
| CAS Number | 38821-53-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cephradine; Cefradine; 38821-53-3; Cephradin; Anspor |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | RDLPVSKMFDYCOR-UEKVPHQBSA-N |
| InChl Code | InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 |
| References |
3D Conformer.
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