About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Cefpodoxime proxetil is an oral prodrug converted in vivo to cefpodoxime. The active cephalosporin binds PBPs and inhibits cell-wall peptidoglycan crosslinking in gram-negative and gram-positive organisms. The proxetil ester significantly improves oral absorption and systemic exposure.
Benefits and advantages
Used in oral lactam PK research, respiratory-pathogen studies, community-infection modelling, lactamase-resistance investigations, cephalosporin SAR profiling, and prodrug-hydrolysis studies.
Side effects and risks
Risks include GI upset, hypersensitivity, dysbiosis, hepatic enzyme elevation and rare haematologic changes. Handle with routine antimicrobial safety measures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H27N5O9S2 |
|---|---|
| Molecular Weight | 557.6 g/mol |
| CAS Number | 87239-81-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cefpodoxime proxetil; Vantin; 87239-81-4; Banan; Orelox |
| IUPAC/Chemical Name | 1-propan-2-yloxycarbonyloxyethyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| InChl Key | LTINZAODLRIQIX-FBXRGJNPSA-N |
| InChl Code | InChI=1S/C21H27N5O9S2/c1-9(2)33-21(30)35-10(3)34-19(29)15-11(6-31-4)7-36-18-14(17(28)26(15)18)24-16(27)13(25-32-5)12-8-37-20(22)23-12/h8-10,14,18H,6-7H2,1-5H3,(H2,22,23)(H,24,27)/b25-13-/t10?,14-,18-/m1/s1 |
| References |
3D Conformer.
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