CEFADROXIL
Cefadroxil is a first‑generation cephalosporin with broad gram‑positive activity. Benefits include good oral absorption. Side effects include GI upset and allergic reactions.
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Product Description
Mechanism of Action
Cefadroxil is a first-generation cephalosporin antibiotic with strong gram-positive activity. It inhibits PBPs, preventing cell-wall crosslinking and peptidoglycan formation. Cefadroxil exhibits extended half-life due to enhanced renal tubular reabsorption, allowing less frequent dosing.
Benefits and Advantages
Used in gram-positive susceptibility testing, β-lactam structure–activity research, PBP-binding assays, oral cephalosporin pharmacokinetic modelling and staphylococcal cell-wall studies.
Side Effects and Risks
Risks include hypersensitivity, diarrhoea, dysbiosis, eosinophilia, and rare hepatic effects. Handle as a β-lactam antibiotic.
Datasheet
| Molecular Formula | C16H17N3O5S |
|---|---|
| Molecular Weight | 363.4 g/mol |
| CAS Number | 50370-12-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cefadroxil; 50370-12-2; Cephadroxil; Cefadroxil anhydrous; Cefadroxilo |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | BOEGTKLJZSQCCD-UEKVPHQBSA-N |
| InChl Code | InChI=1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1 |
| References |
3D Conformer.
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