CARBACHOL
Carbachol is a cholinergic agonist used in ophthalmology to induce miosis and reduce intraocular pressure. Side effects include blurred vision, sweating, and headache. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Carbachol is a nonselective cholinergic agonist resistant to acetylcholinesterase hydrolysis. It activates both muscarinic and nicotinic receptors, causing strong parasympathomimetic effects: miosis, increased smoothmuscle contraction, glandular secretion and reduced intraocular pressure by enhancing aqueoushumor outflow. It is significantly longer acting than acetylcholine.
Benefits and advantages
Used in receptorbinding studies, muscarinic/nicotinic signalling research, GImotility models, smoothmuscle contraction assays, ophthalmiccholinergic investigations and neurotransmission pathway mapping.
Side effects and risks
Risks include bradycardia, bronchospasm, abdominal cramps, sweating and hypotension. Handle under cholinergicagonist precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C6H15ClN2O2 |
|---|---|
| Molecular Weight | 182.65 g/mol |
| CAS Number | 24353-61-5 |
| Storage Condition | Store in airtight containers. Protect from light. |
| Solubility | 1 g in 1 ml water |
| Purity | Purity information is available upon request (COA). |
| Synonym | carbachol; 51-83-2; Miostat; CARBACHOL CHLORIDE; Carbamylcholine chloride |
| IUPAC/Chemical Name | 2-carbamoyloxyethyl(trimethyl)azanium chloride |
| InChl Key | AIXAANGOTKPUOY-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H |
| References |
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