BIPERIDEN

Biperiden is an anticholinergic reducing tremor and rigidity in Parkinsons disease. Side effects include dry mouth, blurred vision, constipation, and confusion. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 521677dd9f8a Category: Tag:

Product Description


Mechanism of action

Biperiden is an anticholinergic agent that selectively antagonises central muscarinic M receptors, reducing cholinergic activity in the striatum. This restores dopaminergiccholinergic balance and is used to model or treat extrapyramidal symptoms associated with dopamine antagonism. It also exhibits mild antihistaminic and antispasmodic activity.

Benefits and advantages

Used in Parkinsons-disease research, extrapyramidal-symptom modelling, central muscarinic-receptor studies, cholinergic signalling investigations and anticholinergic SAR development.

Side effects and risks

Risks include cognitive impairment, dry mouth, blurred vision, urinary retention, tachycardia and central anticholinergic syndrome. Handle with CNS-active antimuscarinic precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C21H29NO

Molecular Weight

311.5 g/mol

CAS Number

514-65-8

Storage Condition

Biperiden hydrochloride tablets should be stored in tight, light-resistant containers at 15-30 °C.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

biperiden; 514-65-8; Biperidene; Biperidine; Biperideno

IUPAC/Chemical Name

1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol

InChl Key

YSXKPIUOCJLQIE-UHFFFAOYSA-N

InChl Code

InChI=1S/C21H29NO/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/2381;

3D Conformer.

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