BEZAFIBRATE

Bezafibrate is a lipidlowering agent activating PPAR receptors to reduce triglycerides and improve HDL. Side effects include GI upset, muscle pain, and rare hepatotoxicity. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 054213628930 Category: Tag:

Product Description


Mechanism of action

Bezafibrate is a panPPAR agonist activating PPAR, PPAR and PPAR to varying degrees. It modulates lipid metabolism by increasing fattyacid oxidation, reducing triglycerides, improving insulin sensitivity and lowering VLDL production. It also influences inflammatory signalling and glucose homeostasis.

Benefits and advantages

Important in metabolicdisease research, dyslipidaemia modelling, PPARtarget discovery, mitochondrial fattyacid oxidation studies, insulinresistance models and cardiometabolic investigations.

Side effects and risks

Risks include hepatic enzyme elevations, GI symptoms, gallstone formation and rare myopathy. Handle with metabolicmodulator precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C19H20ClNO4

Molecular Weight

361.8 g/mol

CAS Number

41859-67-0

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

1.55e-03 g/L

Purity

Purity information is available upon request (COA).

Synonym

bezafibrate; 41859-67-0; Bezalip; Bezafibrato; Bezatol SR

IUPAC/Chemical Name

2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid

InChl Key

IIBYAHWJQTYFKB-UHFFFAOYSA-N

InChl Code

InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)

References

https://pubchem.ncbi.nlm.nih.gov/compound/39042;

3D Conformer.

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