BEZAFIBRATE
Bezafibrate is a lipidlowering agent activating PPAR receptors to reduce triglycerides and improve HDL. Side effects include GI upset, muscle pain, and rare hepatotoxicity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Bezafibrate is a panPPAR agonist activating PPAR, PPAR and PPAR to varying degrees. It modulates lipid metabolism by increasing fattyacid oxidation, reducing triglycerides, improving insulin sensitivity and lowering VLDL production. It also influences inflammatory signalling and glucose homeostasis.
Benefits and advantages
Important in metabolicdisease research, dyslipidaemia modelling, PPARtarget discovery, mitochondrial fattyacid oxidation studies, insulinresistance models and cardiometabolic investigations.
Side effects and risks
Risks include hepatic enzyme elevations, GI symptoms, gallstone formation and rare myopathy. Handle with metabolicmodulator precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C19H20ClNO4 |
|---|---|
| Molecular Weight | 361.8 g/mol |
| CAS Number | 41859-67-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 1.55e-03 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | bezafibrate; 41859-67-0; Bezalip; Bezafibrato; Bezatol SR |
| IUPAC/Chemical Name | 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid |
| InChl Key | IIBYAHWJQTYFKB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24) |
| References |
3D Conformer.
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