BETAMETHASONE DIPROPIONATE MICRONIZED
Betamethasone dipropionate micronized is a highpotency topical corticosteroid that decreases inflammation and itching. Benefits include rapid symptom relief. Side effects include skin atrophy, dryness, and potential systemic absorption with long-term use. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Betamethasone dipropionate is a highpotency glucocorticoid ester with superior lipophilicity, allowing deep dermal penetration. It acts via glucocorticoid receptor binding after enzymatic activation, reducing inflammatory mediators, immune-cell recruitment and vasodilation. Micronisation enhances topical absorption and bioavailability.
Benefits and advantages
Applied in dermatology research, inflammatory-skin-disease modelling, corticosteroid potency comparison studies, receptor-activation assays and transdermal-delivery investigations. Its long dermal residence time makes it a reference agent for high-potency topical steroids.
Side effects and risks
Risks include skin thinning, HPA-axis suppression, telangiectasia, irritation, and systemic absorption at high doses. Handle as a high-potency steroid with dermal-protection PPE.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C28H37FO7 |
|---|---|
| Molecular Weight | 504.6 g/mol |
| CAS Number | 5593-20-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | BETAMETHASONE DIPROPIONATE; Diprosone; Diprolene; 5593-20-4; Alphatrex |
| IUPAC/Chemical Name | Betamethasone dipropionate |
| InChl Key | ZJQYJRMOBKXWFG-QWACKRBNSA-N |
| InChl Code | InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 |
| References |
3D Conformer.
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