AMPICILLIN
Ampicillin acts by inhibiting bacterial cell wall synthesis and is used for respiratory, urinary, and GI infections. Side effects include diarrhea, rash, and hypersensitivity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Ampicillin acts by binding to PBPs and inhibiting bacterial cell wall transpeptidation. It is active against many Gram-positive organisms and selected Gram-negative bacilli.
Benefits and advantages
Serves as a benchmark lactam in microbiology, genetic plasmid selection (ampresistance markers), and resistance mechanism studies.
Side effects and risks
Hypersensitivity, GI disturbance, rash and rare hepatic dysfunction. Laboratory PPE required.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C16H19N3O4S |
|---|---|
| Molecular Weight | 349.4 g/mol |
| CAS Number | 69-53-4 |
| Storage Condition | Ampicillin capsules and powder for oral suspension should be stored in tight containers @ 15-30 °C. Following reconstitution, oral suspensions of either anhydrous ampicillin or ampicillin trihydrate should preferable be refrigerated @ 2-8 °C but are stable for 7 days @ room temperature or 14 days @ 2-8 °C. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ampicillin; 69-53-4; Aminobenzylpenicillin; Ampicillin acid; Ampicilline |
| IUPAC/Chemical Name | (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| InChl Key | AVKUERGKIZMTKX-NJBDSQKTSA-N |
| InChl Code | InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1 |
| References |
3D Conformer.
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