AMINOPHYLLINE HYDRATE

Aminophylline hydrate has identical bronchodilatory effects to aminophylline and is used for acute airway obstruction. Side effects include CNS stimulation, tachycardia, and gastrointestinal upset. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 8a2fc7b71acc Category: Tag:

Product Description


Mechanism of action

Aminophylline hydrate exhibits identical pharmacodynamic behaviour to anhydrous aminophylline. The hydrate form alters crystal lattice properties, hygroscopicity and dissolution rates but does not change its fundamental action as a PDE inhibitor and adenosine receptor antagonist.

Benefits and advantages

Chosen for formulation stability in aqueous solutions, aminophylline hydrate is valuable in analytical chemistry, comparative solubility studies and parenteral formulation development.

Side effects and risks

Its toxicological profile mirrors all methylxanthinesrisk of cardiac arrhythmias, CNS excitation and gastrointestinal irritation. Laboratory-grade handling precautions are mandatory.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C16H26N10O5

Molecular Weight

438.44 g/mol

CAS Number

76970-41-7

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Aminophylline hydrate; aminophylline monohydrate; UNII-Y7E0LU9ZMS; Y7E0LU9ZMS; DTXSID40227754

IUPAC/Chemical Name

bis(1,3-dimethyl-7H-purine-2,6-dione);ethane-1,2-diamine;hydrate

InChl Key

FCDVEQMNVIBKAU-UHFFFAOYSA-N

InChl Code

InChI=1S/2C7H8N4O2.C2H8N2.H2O/c2*1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4;/h2*3H,1-2H3,(H,8,9);1-4H2;1H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/16218860;

3D Conformer.

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