AMINOPHYLLINE HYDRATE
Aminophylline hydrate has identical bronchodilatory effects to aminophylline and is used for acute airway obstruction. Side effects include CNS stimulation, tachycardia, and gastrointestinal upset. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Aminophylline hydrate exhibits identical pharmacodynamic behaviour to anhydrous aminophylline. The hydrate form alters crystal lattice properties, hygroscopicity and dissolution rates but does not change its fundamental action as a PDE inhibitor and adenosine receptor antagonist.
Benefits and advantages
Chosen for formulation stability in aqueous solutions, aminophylline hydrate is valuable in analytical chemistry, comparative solubility studies and parenteral formulation development.
Side effects and risks
Its toxicological profile mirrors all methylxanthinesrisk of cardiac arrhythmias, CNS excitation and gastrointestinal irritation. Laboratory-grade handling precautions are mandatory.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C16H26N10O5 |
|---|---|
| Molecular Weight | 438.44 g/mol |
| CAS Number | 76970-41-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Aminophylline hydrate; aminophylline monohydrate; UNII-Y7E0LU9ZMS; Y7E0LU9ZMS; DTXSID40227754 |
| IUPAC/Chemical Name | bis(1,3-dimethyl-7H-purine-2,6-dione);ethane-1,2-diamine;hydrate |
| InChl Key | FCDVEQMNVIBKAU-UHFFFAOYSA-N |
| InChl Code | InChI=1S/2C7H8N4O2.C2H8N2.H2O/c2*1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4;/h2*3H,1-2H3,(H,8,9);1-4H2;1H2 |
| References |
3D Conformer.
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